The Cellular Mechanisms of Stress
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Jodi Duval, and Dr. Allen Bookatz explore what happens inside the cell when...
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Read Your Genes! APOE4, Brain Health, and Longevity
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Jup Kuipers, Boomer Anderson, Dr. Allen Bookatz, and Dr. Scott Sherr explore...
Why You're Frozen in Survival Mode: Understanding CDR
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, and Jodi Duval sit down to discuss...
Can Creatine Protect the Brain from Sleep Deprivation?
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Dr. Jup Kuipers explore how acute...
The Real Cause of Endotoxemia: Leaky Gut Explained
In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers explore a misunderstood cause...
Is Your Cellular Membrane Leaking the Fuel That Keeps You Going? (Why NAD+ Isn't Enough)
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Jodi Duval explore one of the...
Dr. Dominic D'Agostino | What Ketones Actually Do to Your Body
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr sits down with Dr. Dominic D'Agostino, the premier researcher in ketogenic metabolic therapies....
Metformin is Poisoning Your Cells
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Jodi Duval, and Dr. Jup Kuipers take...
The Gut-Brain-Microbiome Axis: Understanding Depression, Serotonin, & Probiotics
In this episode of the Health Optimization Medicine Podcast, Dr. Ted Achacoso, Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Jup Kuipers, and Jodi Duval take...
Why You Can’t Out-Supplement a Dysregulated Nervous System
In this episode of the Health Optimization Medicine Podcast, Dr. Allen Bookatz, Dr. Ted Achacoso, and Jodi Duval tackle the widespread trend of supplement fatigue.
Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox
In this episode of the Health Optimization Medicine Podcast, our faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, Dr. Allen Bookatz, and Jodi Duval,...
The HRV Paradox: Why Tracking Your Sleep Makes It Worse
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, and Jodi Duval) tackles one...
Decoding the Holobiont: The Ecosystem of Ecosystems
In this special in-person roundtable recorded in Washington, D.C., the HOMeHOPe faculty sit down to decode one of the most important perspective shifts in modern...
Is "Fiber-Maxxing" Ruining Your Gut?
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty tackles one of the most misunderstood topics in modern nutrition: fiber. Moving past...
Why Aging May Be the Root Cause of Chronic Disease
In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz...
Polyethylene Glycol (PEG): A Usage Guide
One of the most frequently asked questions we get at Troscriptions is why we use polyethylene glycol (PEG for short) as the base/suspension media for...
Depression Isn't Just a Serotonin Deficiency: What's Really Going On in the Brain?
This article goes past the serotonin headline and into what current neuroscience actually shows: a set of biological systems, including stress, inflammation, brain plasticity, and...
GABA Deficiency and Brain Fog: Understanding the Link Between Inhibitory Signaling and Cognitive Function
GABA helps regulate the neural activity involved in attention, memory, stress, and sleep. But does impaired GABA signaling actually cause brain fog? Here’s what the...
The Role of Inflammation and Cytokines in Depressive Symptoms: Understanding the Mind-Immune Connection
Inflammation may contribute to depressive symptoms in some people by affecting neurotransmitters, neuroplasticity, and communication between the immune system and brain. Here’s what the research...
Salidroside and Cognitive Function: Focus, Mental Clarity, and Brain Fog
Salidroside may support cognitive resilience by influencing pathways involved in stress, inflammation, oxidative damage, and brain function. Explore what the research says about its potential...
Why GABA Makes Some People More Anxious, Not Less
GABA is known as the brain’s calming neurotransmitter, but for some people, increasing GABA activity can have the opposite effect. Learn five biological reasons behind...
The Connection Between GABA Deficiency and Chronic Stress: Understanding HPA Axis Dysregulation and Burnout
Although GABA deficiency is rarely the sole cause of chronic stress or burnout, disruptions in GABA signalling appear to play an important role in the...
How Your Day Shapes the Biology of Depression: Sleep, Movement, Food, and Light
Depression is shaped by more than brain chemistry alone. This article explores how sleep, movement, food, and light influence the biological systems tied to mood...
Why Alcohol Feels Like Anxiety Relief (Until It Doesn’t): The GABA Rebound Effect Explained
Alcohol’s relationship with anxiety is one of neuroscience’s more ironic stories: a molecule that produces short-term calm through the very same mechanisms that, over time,...
Salidroside and the HPA Axis: Stress Resilience and Cortisol Regulation
This article looks at the relationship between salidroside and the HPA axis, examining how this compound may support healthy cortisol regulation and improve the body’s...
Exploring How GABA Deficiency Contributes to Depression: Excitatory-Inhibitory Imbalance and Stress Overload
This article explores how GABA deficiency may contribute to depression, focusing specifically on excitatory/inhibitory imbalance and stress-related mechanisms of action.
Why Sodium Pulls Water In, and Potassium Keeps It There: The Chemistry Behind Hydration Packs
This article follows the journey of water through the body, explaining how sodium and potassium work together to move fluid from the gut into the...
Mechanisms of Salidroside in the Brain: Neuroprotection, Anti-Fatigue, and Stress Response Modulation
Salidroside can cross the blood-brain barrier and influences multiple pathways involved in neuronal health, energy production, and the body's response to stress, making it an...
How Antidepressants (SSRIs) Actually Work: Beyond the “Serotonin Imbalance” Theory
Although SSRIs increase serotonin levels quickly, current research suggests their therapeutic effects involve broader changes in brain function, neuroplasticity, and stress-related biology that develop over...
From Gut to Cell: How Electrolytes and Glucose Improve Water Absorption
Water absorption depends on more than water alone — electrolytes and glucose work together through specialized transport systems in the gut to help move fluid...
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