Learning & education
Agmatine is a naturally occurring biogenic amine produced by decarboxylation of the amino acid arginine via the enzyme arginine decarboxylase. Its multifaceted neurochemical effects have positioned it as a potential modulator of mood and anxiety symptoms, though many questions remain about its clinical utility.
If you’ve ever typed “is kava bad for your liver?” into a search bar, you know exactly how chaotic the results can be. On one side, you’ll find headlines sounding the alarm; on the other, centuries of safe, deeply rooted traditional use across the South Pacific.
Kava first came to the West in the form of kava bars, where patrons were served various drinks with kava in them as an alternative to alcohol. It was also used as a short-acting anesthetic because of its well-known mild numbing effect on mucosal surfaces, a property much attributed to the activity of kava extract.
In this article, we break down what recent science reveals about vitamin B3, its role in supporting brain energy, and whether it truly impacts cognitive performance.
This article explores the biology, proposed mechanisms, the human and preclinical evidence behind agmatine sulfate with respect to neuropathic pain, typical doses used in published work, safety signals, and practical considerations for clinicians and patients.
This article looks to summarize the evidence on agmatine sulfate's mechanisms and potential benefits, known and possible side effects, practical dosing ranges used in studies and commercial supplements, as well as safety considerations.