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Learning & Education

The whole world is getting more anxious by the day. According to recent statistics, up 33.7% of people will be affected by an anxiety disorder during their lifetime [2] and there are currently 264 million people impacted globally [3].  

In 2019, the percentage of patients taking anti-anxiety medication was around 10% in females over 45, and around 5% in males, according to Statista.com. And since the pandemic, these rates have skyrocketed. Currently there are 50 million Americans taking mental health medications. This was an increase in 20% in just one year, from 2020 to 2021 according to the CDC

In today’s article, we will take a look at the different neurotransmitters are involved in the anxiety response.

  • 7 min read

Yes indeed. They are PONs + pyschoplastogens! Let us explain....

The use of classical psychedelic substances for therapeutic purposes has surged in recent years. Although in its infancy, research has also alluded to the potential benefits of ‘microdosing’ psychedelics for health and wellness, namely by lowering depression, anxiety, and stress as well as enhancing cognitive performance [2].  

Today’s article poses the following questions: is it possible for psychedelics to be nootropics? If so, how? And could the neural plasticity-altering effects of these well-known drugs be harnessed to enhance brain function (i.e are they pyschoplastogens)? 

But first...what are nootropics again? 

  • 8 min read
Programs! Get your programs! In this article, we’re going to take a look at the default mode network (DMN), also known as the default state network + ways to modulate its activity! 
  • 8 min read

Whether in the boardroom, bedroom, on the athletic pitch, hiking Everest, fluffing (google it), or trying to finish an ultramarathon, can we all agree that performance kind of of a big deal?!  

Let's talk Performance Optimization Nootropics (PONs)! 

  • 6 min read
First-pass metabolism, otherwise known as the ‘first-pass effect’. This phenomenon relates mainly to drugs and other supplements that are consumed orally. The concentration of a drug or supplement that we ingest is often not the amount that is eventually seen in the blood (systemic circulation).
  • 9 min read
How well do you methylate? Where do these methyl groups come from? And why should you care? Well, Tro Nation, today’s article explores methylation in detail because, like Hansel from Zoolander, methylation is just “so hot right now”. 
  • 10 min read
Get out your eggs! In this article, we will explore an important neurotransmitter in the body and brain called acetylcholine (ACh). While also functioning as a classical neuromodulator, ACh is similar to norepinephrine, serotonin, and dopamine, in that it cannot cross the blood-brain barrier. 
  • 9 min read
In today’s article, we are going to cover the “fight or flight” (or “oh sh*t there’s a bear”) catecholamine and neurotransmitter known as norepinephrine (NE). As with gamma-aminobutyric acid (or GABA), serotonin, and dopamine, norepinephrine can’t cross the blood-brain barrier.
  • 9 min read

In today’s article, we are going to explore the well-known, indispensable, and now kind of infamous neurotransmitter dopamine. As with gamma-aminobutyric acid (or GABA) and serotonin, dopamine can’t cross the blood-brain barrier. 

  • 7 min read
Before starting Troscriptions in 2019, we did a huge amount of research into the history of nootropics, the many varieties out there, and we tried many (many!) along the way. Although our brains usually enjoyed the ride (with some notably terrible exceptions), it became clear that no one could agree what a nootropic really was and what it wasn’t.   
  • 6 min read
In today’s article, we are going to explore one of the most well-known and important neurotransmitters – serotonin. As with gamma-aminobutyric acid, or GABA, serotonin can’t cross the blood-brain barrier to do its work.
  • 7 min read
Flashy news articles alert! Did you hear that biohackers and optimal performers like Ben Greenfield, the Biohacker Babes (our friends Lauren and Renee), and many others from the Tro Nation are using “fish tank cleaner” to reverse aging and optimize their mitochondria? 
  • 4 min read

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