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Reducing GABA-A receptor signaling can have profound effects on the central nervous system, leading to significant physiological and neurological consequences, including increasing neuronal excitability, altered pain perception, mood changes, increased anxiety, and seizures.
How do GABA supplements exert their action? Is the observed effect merely a result of the placebo effect? Do these supplements work through peripheral mechanisms outside the brain? Or can GABA actually cross the blood-brain barrier?
The goals of this article are to explore the effect of GABA on muscle protein synthesis and evaluate its use as an ergogenic aid for the maintenance or enhancement of skeletal muscle mass to support optimal health.
Adenosine is a naturally occurring compound in the body that plays a crucial role in regulating sleep. It is a neurotransmitter that builds up in the brain throughout the day and promotes sleepiness. Caffeine, a widely consumed stimulant, works by blocking the effects of adenosine.
Adenosine plays a role in a wide range of physiological processes, such as sleep regulation, angiogenesis, and immune system modulation. It also shows interesting properties in humans as a local messenger in the skin.
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