Learning & education
Melatonin is well-known for its modulation of the circadian rhythm through signaling pathways involving its two G protein-coupled receptors. However, melatonin is involved in many other mechanisms and represents therapeutic opportunities for different conditions, including anxiety and depression.
Given the immense burden of depression and PTSD, new and innovative therapies are required to help address these challenges to global public health. This article aims to provide information on ketamine troches and their proposed mechanistic impact on depression and PTSD.