Research from the turn of the century proposed that reduced forms of honokiol might yield enhanced anxiolytic activity compared with its parent compound [12,13]. The most promising of these was dihydrohonokiol-beta (DHH-B or 3'-(2 propenyl)-5-propyl-(1,1'-biphenyl)-2,4'-diol), a partially reduced honokiol derivative .
Honokiol is a natural compound derived from the bark and seed cones of the Magnolia tree. It has a long history of use in traditional medicine, particularly in East Asia. It has gained significant attention in recent years due to its potential therapeutic properties, especially as an allosteric modulator of GABA receptors.
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