Learning & education: psychedelic therapy

How does melatonin affect psychedelic therapy?
Aug 21, 2025
In this article, we will look at what’s known about combining melatonin with common psychedelics, based on the current evidence available. We discuss how melatonin might enhance, dampen, or otherwise alter psychedelic effects, how it could influence sleep and neuroplasticity, and what gaps remain in the research base.