Behind the science

What's a buccal troche?

At Troscriptions®, we use one of the most unique drug/supplement delivery methods on the planet: the buccal troche. A buccal troche is a small lozenge that dissolves between your upper cheek and gums. It has been used for decades by compounding pharmacists for drugs like oxytocin, ketamine, hormone replacement, and others.

Dr. Ted and the physicians on the Troscriptions® team have used buccal troches for years in this context and, due to their many advantages, decided to be the first company ever to scale their production for the non-prescription market. 

Guy using buccal troche between cheek and gum
Guy smiling while holding a troche

Key benefits

  • Easy to use
  • Rapid-acting
  • Preserve bioavailability
  • Have a direct route to the brain via cheek mucosa
  • Have been used safely and effectively by compounding pharmacists for decades (i.e., hormone replacement and ketamine troches)

In addition, buccal troches at Troscriptions® are:

  • Precision dosed 
  • Pharmaceutical-grade
  • Physician formulated 
  • Made in a GMP-compliant facility 
  • Scored into quarters (so each troche can be easily cut into four individual doses for easy titration)

The buccal troche difference

Watch our quick explainer

WHAT IS A TROCHE

TROCHE

  • Fast onset
  • Higher bioavailability
  • Flexible dosing

CAPSULE

  • Slow onset
  • Lower absorption
  • Less flexible dosing

Calibrate your dose of Just Blue

Follow these steps

  • Choose your starting point

    Decide on your starting dose and, if needed, cut the troche accordingly.

  • Find the sweet spot. Extended

    Gently place the troche between your gum and upper cheek. Alternatively, because Methylene Blue is highly bioavailable, you can also swallow it on an empty stomach.

  • Patience is key

    Allow the troche to dissolve completely. Onset will be 15 to 20 minutes if used as a buccal troche and 60 to 90 minutes if swallowed.

  • Feel the shift

    Soon you'll feel methylene blue's transformational effects as it powers up your cells.

  • Unlock energy and resilience

    Just Blue will brighten your focus, boost your mood, your energy, and your endurance.

Learn more about troches

Troche medications and lozenges: the history and differences

The earliest precursor to lozenges dates back to as early as 1000 BC in Egypt. These ancient cough drop candies were made from honey, herbs, and spices to help soothe the throat. During the 19th century, heroin and morphine were added to suppress coughing (we are not kidding!). There have been many evolutions of the lozenge since then, including the famed Swiss selling Ricola to the masses (while yodeling).Troche medications were developed from lozenges in the 20th century for more rapid onset and more precise and reliable dosing. They remain in use today by compounding pharmacies worldwide.
Don't swallow your drugs! (if there's a buccal troche for it).

When you swallow your supplements or drugs, they are digested in the stomach and small intestines, absorbed through the lining of the gut, and then pass through the liver in a process called first-pass metabolism.

First of all, this process takes a while. For most people, this will take at least 30 minutes but can be delayed up to 2 hours.

Second of all, first-pass metabolism decreases compound bioavailability (i.e. the proportion of a drug or other substance that enters the circulation when introduced into the body that has an active effect), often dramatically.

Buccal troches, in contrast, bypass first-pass metabolism and directly infuse their ingredients into the bloodstream via the highly vascular cheek mucosa. This means you’ll have a reliable onset of action in 15 to 30 minutes (not up to 2 hours when ingested) and none of the troche ingredients will lose their potency.

Plus, as a bonus, troche ingredients have a quick path to the brain given their proximity. This is game-changing for nootropics that turn your brain on and just as beneficial for troches that help you relax and sleep.

Find the perfect troche for you

Discover the ideal troche to support you. Whether you need a boost for productivity, mental clarity, or relaxation, we have the formula for you.
Take our quick quiz to find your perfect match!

Find my troche now

Endorsed by leading healthcare professionals

  • Dr. Amie Hornaman

    Dr. Amie Hornaman

    Founder, The Institute for Thyroid and Hormone Optimization
    I've suffered with sleep issues since I was 25. So I said, "I'm going to use Tro Zzz." So I took a half the other night... damn, I slept well. It worked really, really well. So I'm a believer now.

  • Scott Porter, PharmD

    Owner of Sandpoint Super Drug
    I have tried the product and it works great! Positive energy and focus while at work. I had a pounding headache the day I took a 4mg dose and the headache was gone immediately. Lots of my patients are benefiting too.

  • Dr. Stephanie Rimka, DC

    World-Renowned Brain Optimization Specialist
    Troscriptions has been integral in helping my patients recover from a variety of conditions that have stolen their energy and cognitive capacity. I’m thrilled by how many patients successfully transition off various medications with their help.
  • Ashley Beckman

    Dr. Ashley Beckman

    Doctor of Chinese Medicine & Acupuncture
    Troscriptions products have been game-changing in my clinical practice. Having tried numerous products, Troscriptions is the only brand that consistently receives glowing feedback from my patients and truly moves the needle on their health challenges, sometimes in only a few days of taking them.

Shop our troches