Learning & education: Aging
Starting from the very beginning of our existence, the process of aging initiates. It involves the deterioration of cellular structures, gene regulation, and DNA sequences, leading to the aging of individual cells and entire organisms. It is estimated that by 2050, the number of people aged over 80 will triple globally [1].
More than a decade ago, a pathbreaking discovery showed for the first time that mature mouse somatic cells could be reprogrammed into pluripotent stem cells (i.e., make them young again). The discovery was made by using the forced expression of four transcription factors: Oct4, Sox2, Klf4, and c-Myc.
Aging is one of those simple facts of life – it affects us all. It is marked by the inevitable decline in physiological function and an increased risk of disease... and lots of wrinkles, unless you live in South Korea, the plastic surgery capital of the world [1,2]. There are, however, some very distinct differences between chronological aging (your age in terms of years) and biological aging.
AI-generated responses are for informational purposes only and do not constitute medical advice. Accuracy, completeness, or timeliness are not guaranteed. Use at your own risk.
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