Learning & education: Endocannabinoid System
The endocannabinoid system serves to modulate neurotransmission at inhibitory and excitatory synapses in the brain, specifically in brain regions associated with the regulation of emotions, motivation, pain, and cognition [10-14]. Our knowledge of this system has broadened considerably in recent decades and its discovery represents a hallmark in neuroscience.
Anandamide is a neurotransmitter of the endocannabinoid system that is derived from arachidonic acid-containing membrane lipids and has numerous biological functions. Its effects are primarily mediated by the cannabinoid receptors CB1 and CB2, and the vanilloid TRPV1 receptor.
Even though cannabis has accompanied humans for almost 5000 years, it was not until recently that its mechanism in our bodies and related main actors were revealed. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most known active compounds in cannabis. These exocannabinoids interfere with the regular neuron communication system by mimicking natural endocannabinoids, internal compounds produced in our body.
If you’re a fan of all things cannabis, you’ve probably heard about the endocannabinoid system (ECS) — the homeostatic superhero of our bodies that regulates everything from mood to appetite. But did you know that the ECS also has a hand in something called neurogenesis?
Did you know that because of cannabis, getting high on your own supply has never been easier? It's all because of our body's endocannabinoid system (ECS), a major regulatory system, which was discovered because people love their cannabis... and have for almost 5000 years.
The ECS is a biological system composed of endocannabinoids (cannabis-like cannabinoids manufactured by the body), neurotransmitters, cannabinoid receptors, and receptor proteins. The ECS serves a major role in regulating and balancing many processes in the body, including the immune response, communication between cells, appetite, metabolism, memory, hormonal response, your dance moves (just kidding), and much more.
AI-generated responses are for informational purposes only and do not constitute medical advice. Accuracy, completeness, or timeliness are not guaranteed. Use at your own risk.
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