Learning and Education

Have you ever felt exhaustion dragging at your eyelids, only to find yourself wide awake staring at the ceiling as you lie in bed, not feeling sleepy at all despite...

Melatonin is well-known for its modulation of the circadian rhythm through signaling pathways involving its two G protein-coupled receptors. However, melatonin is involved in many other mechanisms and represents therapeutic...

GABA, the natural brain brake, helps tone down neural activity, offering a pocket of serenity among ruminations and worries. Ashwagandha is a gift from Ayurveda that acts as a protective...

In this article, we will look at six common medications and their potential to fuel anxiety. The medications discussed here range from beta-blockers, often used for cardiovascular conditions, to hormonal...

The endocannabinoid system serves to modulate neurotransmission at inhibitory and excitatory synapses in the brain, specifically in brain regions associated with the regulation of emotions, motivation, pain, and cognition [10-14]. Our...

The use of psychedelics for their potential cognitive and mental health benefits is a topic that has gained attention in recent years. Psychedelics like LSD, psilocybin, DMT, ketamine, and MDMA...

Research from the turn of the century proposed that reduced forms of honokiol might yield enhanced anxiolytic activity compared with its parent compound [12,13]. The most promising of these was...

Anandamide is a neurotransmitter of the endocannabinoid system that is derived from arachidonic acid-containing membrane lipids and has numerous biological functions. Its effects are primarily mediated by the cannabinoid receptors CB1 and...

Honokiol is a natural compound derived from the bark and seed cones of the Magnolia tree. It has a long history of use in traditional medicine, particularly in East Asia....

Nowadays, cannabis is a popular topic in the news and on social media. You may have come across articles or blogs discussing compounds called cannabinoids that are present in cannabis...

Even though cannabis has accompanied humans for almost 5000 years, it was not until recently that its mechanism in our bodies and related main actors were revealed. Tetrahydrocannabinol (THC) and cannabidiol (CBD)...

New research evidence suggests that meditation can modulate brain activity, specifically via the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) [3-6]. Though this may perhaps not be surprising to devotees of the practice, in...

The cell danger response (CDR) may just be the most important cellular response that you've never heard of… until now. Well, unless it was in a Mystical song from the the year 2000. The...

Anxiety presents a considerable burden to healthcare services and infrastructure globally, with the annual cost of anxiety disorders estimated at $42.3 billion ($1542 per patient) in 1990 [4]. This article...

Stress management is an essential skill to develop to ensure optimal health and well-being. The ability to rapidly de-stress is an important one, in order to hopefully avoid the regular and...