Jodi Duval: Medical Cannabis, the Endocannabinoid System, + Minor Cannabinoids

In this episode of the Smarter Not Harder Podcast, host Boomer Anderson is joined by guest Jodi Duval to give one-cent solutions to life’s $64,000 questions that include:

  • What is the history and role of various components of cannabis, including THC, CBD, and other cannabinoids, in medicine, and how does their research into the impact on the endocannabinoid system pave the way for further exploration in the field?
  • What is the "Entourage Effect" and how does the combined effect of different cannabinoids and terpenes found in cannabis, particularly their anti-inflammatory, anti-depressant, neuro-protective, and sedative effects, indicate the vast potential of cannabis in healthcare?
  • Why is understanding and measuring endocannabinoid tone, which can impact pain threshold, digestion, mood, and sleep, important and how can genetic testing, symptomology, and tracking be used to assess it? What is the significance of working with a knowledgeable practitioner with medicinal cannabis?



What did Boomer discuss with Jodi Duval?

(0:01:03) - Exploring the history and various components of cannabis as a medicine

(0:07:12) - The origins of cannabis use for medicine in Tibet and the potential of cannabis components for various effects

(0:10:24) - The endocannabinoid system, the differences between CB1 and CB2 receptors, and their impact on human health

(0:22:50) - The clinical relevance of the 'Entourage Effect' and the importance of combining cannabinoids for maximum efficacy

(0:34:40) - The insights into the challenges of sourcing quality cannabis and the importance of working with a practitioner 


Find more from Jodi Duval:



Cannabis Module:

Find more from Smarter Not Harder:

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Book: Hope & Healing, The Case for Cannabis by Dr. Joseph Rosado

Ethan Russo:

The Cannabis Conversation | Medical Cannabis | CBD | Hemp Podcast

Cannabis Chemovars

 Zhu H, Wang J, Zhang Z, et al. Cannabihumanindoles from Cannabis with a structural resemblance to human indoles. Nature. 2022 Feb;602(7897):470-475. doi: 10.1038/s41586-021-04387-1. Epub 2022 Jan 26.

Endocannabinoid Deficiency and Migraine (2022)

HOMe/HOPe Cannabis Course

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AI-generated responses are for informational purposes only and do not constitute medical advice. Accuracy, completeness, or timeliness are not guaranteed. Use at your own risk.

Trixie - AI assistant