Learning & education: GABA
Magnesium and GABA form a powerful duo that helps maintain a balanced and healthy brain, contributing to cognitive function, stress resilience, and neurological stability.
In today’s article, we explore GABA and glutamate, touch on the molecular mechanisms underpinning their actions, and their contributions to various physiological and pathological processes.
Agarin is chemically very similar to gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain. GABA is synthesized from glutamate by the enzyme glutamate decarboxylase with pyridoxal phosphate (vitamin B6) as a cofactor.
L-theanine (or N-ethyl-L-glutamine) is an amino acid analog structurally similar to L-glutamate, one of the primary excitatory neurotransmitters in the central nervous system (CNS).
Reducing GABA-A receptor signaling can have profound effects on the central nervous system, leading to significant physiological and neurological consequences, including increasing neuronal excitability, altered pain perception, mood changes, increased anxiety, and seizures.
How do GABA supplements exert their action? Is the observed effect merely a result of the placebo effect? Do these supplements work through peripheral mechanisms outside the brain? Or can GABA actually cross the blood-brain barrier?
AI-generated responses are for informational purposes only and do not constitute medical advice. Accuracy, completeness, or timeliness are not guaranteed. Use at your own risk.
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