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Despite the undoubted neurotoxicity and dissociative effects of the fly agaric mushroom, there are several bioactive compounds contained within it that are being examined for their potentially beneficial effects on...

L-theanine (or N-ethyl-L-glutamine) is an amino acid analog structurally similar to L-glutamate, one of the primary excitatory neurotransmitters in the central nervous system (CNS).

Reducing GABA-A receptor signaling can have profound effects on the central nervous system, leading to significant physiological and neurological consequences, including increasing neuronal excitability, altered pain perception, mood changes, increased...

How do GABA supplements exert their action? Is the observed effect merely a result of the placebo effect? Do these supplements work through peripheral mechanisms outside the brain? Or can GABA...

The goals of this article are to explore the effect of GABA on muscle protein synthesis and evaluate its use as an ergogenic aid for the maintenance or enhancement of...

GABA and gabapentin are two fundamentally different compounds that share some important similarities. The goals of this article are to provide some background on each one as well as an overview...

Recent studies have highlighted GABA to be beneficial in several ways, with multiple biological activities of GABA attributed to insulin metabolism [3,4]. Notably, signaling through GABA receptors has been associated with...

GABA plays a critical role in the brain and has potential implications for mental and physical health. Factors causing GABA deficiency can individually or collectively contribute to alterations of the...

GABA, the natural brain brake, helps tone down neural activity, offering a pocket of serenity among ruminations and worries. Ashwagandha is a gift from Ayurveda that acts as a protective...

Glutamate is a naturally occurring amino acid that plays a crucial role in brain function and overall health. As one of the most abundant neurotransmitters in the brain, it is...

The immune system is a vitally important network that integrates organs, cells, and proteins throughout the body to fight infection and protect cells from abnormal changes.

The festive traditions of Christmas, replete with feasts, gift-giving, and elaborate decorations, may have evolved from ancient shamanic practices, particularly those involving Amanita muscaria or the fly agaric mushroom.

Research from the turn of the century proposed that reduced forms of honokiol might yield enhanced anxiolytic activity compared with its parent compound [12,13]. The most promising of these was...

Honokiol is a natural compound derived from the bark and seed cones of the Magnolia tree. It has a long history of use in traditional medicine, particularly in East Asia....

Imagine a beautiful mushroom. Do you see a dome-shaped cap atop a slender stem? Visualize the cap’s color. Is it, perhaps, a deep red adorned with white dots? If so,...