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Research from the turn of the century proposed that reduced forms of honokiol might yield enhanced anxiolytic activity compared with its parent compound [12,13]. The most promising of these was dihydrohonokiol-beta (DHH-B or 3'-(2 propenyl)-5-propyl-(1,1'-biphenyl)-2,4'-diol), a partially reduced honokiol derivative [13].
Testing for serotonin levels in the brain is very difficult. Although blood tests are available for serotonin, doctors tend to diagnose low serotonin based on symptoms, not blood concentrations. In the case of serotonin syndrome (high levels of serotonin caused by medication use), doctors use symptomatology and a thorough assessment of medications to arrive at a diagnosis [14,15].
Serotonin is synthesized through a series of enzymatic reactions, beginning with the essential amino acid tryptophan. Essential amino acids cannot be produced by the body, hence the name, and must therefore be consumed through the food we eat.
Anandamide is a neurotransmitter of the endocannabinoid system that is derived from arachidonic acid-containing membrane lipids and has numerous biological functions. Its effects are primarily mediated by the cannabinoid receptors CB1 and CB2, and the vanilloid TRPV1 receptor.
This fall, we will be releasing Tro+ Blue, our first product available only through Troscriptions practitioners and not for general sale. Each Tro+ Blue troche will have 50 mg of USP methylene blue, and there will be 4 troches per pack.
Serotonin syndrome (SS), or serotonin toxicity [1,2], is a condition that can be potentially life-threatening, and is brought about by the use of serotonergic drugs [3,4]. The term serotonergic simply refers to a substance, compound, or receptor that affects pathways that involve the neurotransmitter serotonin.
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