Learning & education
![Performance Optimization Nootropics (PONs)](http://troscriptions.com/cdn/shop/articles/Performance-Optimization-Nootropics-blog-img.jpg?v=1659327084&width=480)
Whether in the boardroom, bedroom, on the athletic pitch, hiking Everest, fluffing (Google it), or trying to finish an ultramarathon, can we all agree that performance is kind of a big deal?Let's talk Performance Optimization Nootropics (PONs)!
![What is First-Pass Metabolism?](http://troscriptions.com/cdn/shop/articles/What-is-First-Pass-Metabolism-blog-img.jpg?v=1659327503&width=480)
First-pass metabolism, otherwise known as the "first-pass effect." This phenomenon relates mainly to drugs and other supplements that are consumed orally. The concentration of a drug or supplement that we ingest is often not the amount that is eventually seen in the blood (systemic circulation).
![What is Methylation?](http://troscriptions.com/cdn/shop/articles/What-is-Methylation-blog-img.jpg?v=1659327337&width=480)
Methylation is the addition of a methyl group (consisting of one carbon atom bonded to three hydrogen atoms) to a substrate, and it impacts physiology in a number of fundamental ways, including the regulation of gene expression (i.e., epigenetics), RNA processing, modifying heavy meals, modulating the function of an array of different proteins, and much, much more.
![In_Depth_Guide_Acetylcholine](http://troscriptions.com/cdn/shop/articles/The-In-Depth-Guide-to-Acetylcholine-header.jpg?v=1660884585&width=480)
In this article, we will explore an important neurotransmitter in the body and brain called acetylcholine (ACh). While also functioning as a classical neuromodulator, ACh is similar to norepinephrine, serotonin, and dopamine in that it cannot cross the blood-brain barrier.
![In_Depth_Guide_Norepinephrine](http://troscriptions.com/cdn/shop/articles/The_In-Depth_Guide_to_Norepinephrine-blog-img.jpg?v=1656802216&width=480)
In today’s article, we are going to cover the “fight or flight” (or “oh sh*t, there’s a bear!”) catecholamine and neurotransmitter known as norepinephrine (NE). As with gamma-aminobutyric acid (or GABA), serotonin, and dopamine, NE can’t cross the blood-brain barrier.
AI-generated responses are for informational purposes only and do not constitute medical advice. Accuracy, completeness, or timeliness are not guaranteed. Use at your own risk.
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Hi, I'm Trixie👋 You can ask me questions like, "What is Tro Calm?" or "What are the benefits of GABA?"