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First-pass metabolism, otherwise known as the "first-pass effect." This phenomenon relates mainly to drugs and other supplements that are consumed orally. The concentration of a drug or supplement that we...

Methylation is the addition of a methyl group (consisting of one carbon atom bonded to three hydrogen atoms) to a substrate, and it impacts physiology in a number of fundamental...

In this article, we will explore an important neurotransmitter in the body and brain called acetylcholine (ACh). While also functioning as a classical neuromodulator, ACh is similar to norepinephrine, serotonin, and dopamine in that...

In today’s article, we are going to cover the “fight or flight” (or “oh sh*t, there’s a bear!”) catecholamine and neurotransmitter known as norepinephrine (NE). As with gamma-aminobutyric acid (or GABA), serotonin,...

In today’s article, we are going to explore the well-known, indispensable, and now kind of infamous neurotransmitter, dopamine. As with GABA or gamma-aminobutyric acid and serotonin, dopamine can’t cross the blood-brain barrier. 

Before starting Troscriptions in 2019, we did a huge amount of research into the history of nootropics, the many varieties out there, and we tried many of them along the...

In today’s article, we are going to explore one of the most well-known and important neurotransmitters: serotonin. As with gamma-aminobutyric acid, or GABA, serotonin can’t cross the blood-brain barrier to do...

Flashy news articles alert! Did you hear that biohackers and optimal performers like Ben Greenfield, the Biohacker Babes (our friends Lauren and Renee), and many others from the Tro Nation...

One of the most frequently asked questions we get at Troscriptions is why we use polyethylene glycol (PEG for short) as the base/suspension media for our formulas.  There are a...

The ECS is a biological system composed of endocannabinoids (cannabis-like cannabinoids manufactured by the body), neurotransmitters, cannabinoid receptors, and receptor proteins. The ECS serves a major role in regulating and...

One of the most important sets of regulations for consumables is Good Manufacturing Practice (GMP). These regulations ensure that the companies that produce products such as food, cosmetics, pharmaceuticals, supplements, and more...

N-nicotinoyl-GABA is a novel combination of niacin, a form of vitamin B3, and GABA molecularly bound together in a single compound. This combination is BBB permeable, and increases both vitamin B3 and...

The word enlightenment literally means to be “filled with light." Sounds awesome, right? But wait a minute… what kind of light are we talking about? Because if it’s from a...

Cannabidiol (CBD) is certainly no longer the new kid on the block. In the last five years, it has exploded on the market in products that range from shampoos, skin...

Discover the cognitive benefits of nicotine as a nootropic, from improved focus and memory to overall brain health and other positive effects on the brain.