Learning & education
Whether in the boardroom, bedroom, on the athletic pitch, hiking Everest, fluffing (Google it), or trying to finish an ultramarathon, can we all agree that performance is kind of a big deal?Let's talk Performance Optimization Nootropics (PONs)!
First-pass metabolism, otherwise known as the "first-pass effect." This phenomenon relates mainly to drugs and other supplements that are consumed orally. The concentration of a drug or supplement that we ingest is often not the amount that is eventually seen in the blood (systemic circulation).
Methylation is the addition of a methyl group (consisting of one carbon atom bonded to three hydrogen atoms) to a substrate, and it impacts physiology in a number of fundamental ways, including the regulation of gene expression (i.e., epigenetics), RNA processing, modifying heavy meals, modulating the function of an array of different proteins, and much, much more.
In this article, we will explore an important neurotransmitter in the body and brain called acetylcholine (ACh). While also functioning as a classical neuromodulator, ACh is similar to norepinephrine, serotonin, and dopamine in that it cannot cross the blood-brain barrier.
In today’s article, we are going to cover the “fight or flight” (or “oh sh*t, there’s a bear!”) catecholamine and neurotransmitter known as norepinephrine (NE). As with gamma-aminobutyric acid (or GABA), serotonin, and dopamine, NE can’t cross the blood-brain barrier.
In today’s article, we are going to explore the well-known, indispensable, and now kind of infamous neurotransmitter, dopamine. As with GABA or gamma-aminobutyric acid and serotonin, dopamine can’t cross the blood-brain barrier.
AI-generated responses are for informational purposes only and do not constitute medical advice. Accuracy, completeness, or timeliness are not guaranteed. Use at your own risk.
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